Search
Now showing items 71-80 of 352
New Statistical Methods for Integrative Data Analysis and Applications in Biology, Epidemiology and Finance
(2018-09-06)
This dissertation consists of four self-contained chapters where statistical methods for integrative data analysis with applications in biology, epidemiology and finance are introduced and discussed. Chapters 1 and 2 focus ...
Glycomic regulation of human B cells
(2018-09-16)
All leukocytes are coated with a dense layer of carbohydrates called the glycocalyx. Initially believed to serve largely biophysical roles, the glycocalyx is increasingly recognized as a gatekeeper of leukocyte interactions ...
Interpretability Through Interrogation: Fairness and Interpretability in the Context of Criminal Sentencing
(2018-06-29)
In this paper, I will explore the ways in which algorithms such as those used in criminal sentencing determinations can be biased against demographic subgroups and the attempts that have been made to correct this bias. I ...
Intergenerational Transmission of Non-Germline RNAs in Caenorhabditis Elegans
(2018-05-13)
In the model organism Caenorhabditis elegans, double-stranded RNA (dsRNA) capable of silencing genes can be introduced anywhere in the animal and will subsequently travel throughout the body and enter most cells, including ...
Responsive and Dynamic Systems from DNA-Mediated Colloidal Interactions
(2018-09-16)
Grafting DNA oligonucleotides to colloidal particles leads to specific, reversible interactions between those particles. However, these interactions have been used almost exclusively to create non-responsive systems through ...
Essays on Globalization
(2018-05-11)
International trade has vastly changed over the last couple of decades with production processes becoming increasingly fragmented across country borders and production stages. This thesis studies the supply chain networks ...
Family Matters: Tracing the Social Cognitive Development of Kinship Understanding
(2018-05-10)
Kinship provides the major framework for social organization, but when do infants and children develop understanding of these social relationships and how they affect social behaviors? This dissertation proposes that ...
A Whole New Whorl: An Exploration of the Morphology, Genetics, and Ecological Function of the Staminodes of Aquilegia
(2018-05-03)
The organ identity genes that encode the four organs of the canonical floral body plan are well characterized. In contrast, the downstream developmental pathways involved in programming the morphological differences found ...
Mechanistic Studies of First-Row Metal-Mediated and -Catalyzed Reactions
(2018-04-10)
First-row transition metals find growing applications in organic transformations due to their abundance and low cost. In addition, the difference in redox states of first-row metals to those of second or third row metals ...
Probing Nanopore - DNA Interactions With MspA
(2018-05-11)
Nanopores can be used as extremely sensitive instruments to directly measure properties of individual molecules. Progress in the nanopore field has been motivated largely by a desire to sequence DNA quickly and accurately. ...