Now showing items 1-4 of 4
Flagellar Biosynthesis in E.coli Is Regulated by a Cascade of Stochastic Pulses
Genetically identical populations of bacteria can exhibit significant phenotypic heterogeneity even in the absence of environmental variations. In bacteria such as Bacillus and Salmonella, flagellar motility has been found ...
Free Actin and Effects on Lung Macrophage Bacterial Defenses
Actin release into the circulation and extracellular space, with subsequent removal by the actin scavenging protein plasma gelsolin (pGSN), has long been reported in injury and infection. Our laboratory’s recent finding ...
The Role of MreB in Producing Rod-Shaped Bacterial Cells
MreB, an actin homolog, is known to form short, membrane-associated filaments that move circumferentially in rod-shaped bacteria, in association with cell wall-synthesizing enzymes. Despite being essential for rod shape, ...
Clp-Mediated Regulation of the Mycobacterial Cell Cycle
Tuberculosis is currently the most deadly infectious disease worldwide. Given the high rates of treatment failure, new antibiotics are desperately needed. Antibacterial drugs typically target DNA replication, cell growth, ...