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Flagellar Biosynthesis in E.coli Is Regulated by a Cascade of Stochastic Pulses
Genetically identical populations of bacteria can exhibit significant phenotypic heterogeneity even in the absence of environmental variations. In bacteria such as Bacillus and Salmonella, flagellar motility has been found ...
Fitness Tradeoffs, Bimodality, and the Genetics of Natural Variation in Glucose-Galactose Sensing Across Saccharomyces Cerevisiae
In nature, cells must constantly sense their environment and respond appropriately. These cellular “decisions” are implemented by molecular components that can mutate and evolve. How do mutations lead to changes in cellular ...
Circadian Clocks in the Real World: Effects of Dynamic Light Regimes on the Regulation of Circadian Gene Expression in Cyanobacteria
Organisms use internal oscillators to control their physiology in conjunction with the predictable environmental changes of the day/night cycle. However, it is not always clear how internal timing information is used by ...