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Elucidating CTCF-Mediated Regulation of V(D)J Recombination at the Immunoglobulin Heavy Chain Locus
(2017-09-08)
Immunoglobulin heavy (IgH) and light (IgL) chains associate to form the B cell receptor (BCR), which is secreted as an antibody upon B cell activation. Each B cell generates and expresses a unique set of IgH and IgL variable ...