Now showing items 1-3 of 3
Global Signatures of Selection in Humans
This thesis studies the properties and prevalence of natural selection operating on our species on a global or genome-wide scale. It is still not known how negative selection against deleterious mutations operates genome-wide, ...
Finding Cis-Regulatory Regions in Long Noncoding RNA Loci
We currently understand very little about how the genome functions. Up to 80% of the genome is transcribed, but much of biology focuses on the ~1-5% that codes for proteins. This narrow focus leaves many newly cataloged ...
Genomic Analysis of Viral Outbreaks
Due to recent advances in sequencing technologies, genomics has emerged as a powerful tool for combating viral outbreaks. In this dissertation, I show how genomic data can be used to understand the transmission, as well ...