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Competition and Coexistence in Yeast Experimental Evolution
Natural selection gives rise to biodiversity by purging the less-fit among variants that are too similar (a principle known as character displacement), but to predict how fit or different an organism needs to be to survive ...
Single-Molecule Studies of Bacterial Chromosome Organization and Segregation
The bacterial chromosome is dramatically compacted into a subcellular structure called nucleoid. Simultaneously, it must be organized to allow the protein machinery for essential cellular processes to gain access to the ...
DNA Polymerase Exchange and Lesion Bypass in Escherichia Coli
Translesion synthesis (TLS) alleviates replication stalling at DNA lesions. Bypass of lesions by specialized translesion DNA polymerases involves exchange with high-fidelity replicative polymerases. As a consequence of ...