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Semiparametric Methods for Causal Mediation Analysis and Measurement Error
(2015-08-06)
Chapter 1: Since the early 2000s, evidence has accumulated for a significant differential effect of first-line antiretroviral therapy (ART) regimens on human immunodeficiency virus (HIV) treatment outcomes, such as CD4 ...
Improving Reproductive Health: Assessing Determinants and Measuring Policy Impacts
(2016-05-11)
In this thesis, I investigate policies and programs to improve reproductive health. My thesis makes a substantive contribution to reproductive health policy and a methodological contribution to quasi-experimental research. ...
On the Statistical Properties of Epidemics on Networks
(2016-05-09)
One major aim of statistics is to systematically study outcomes of interest in a population by observing the properties of a sample of that population. Some outcomes, such as the total number of people infected in an ...
Policy and Methods in Health Services Research
(2016-09-13)
This dissertation consists of two policy papers and one methods paper, all grounded in applied, empirical health-services research. The first two papers concern the influence of medical underwriting in the market for ...
Evaluating Health Interventions Over Time: Empirical Tests of the Validity of the Single Interrupted Time Series Design
(2016-08-29)
Single interrupted time series (ITS) is a quasi-experimental evaluation design used frequently in the health policy literature. This manuscript investigates the validity of single ITS through two within-study comparisons ...
Statistical Methods for Estimating the Effects of Multi-Pollutant Exposures in Children's Health Research
(2016-09-15)
We develop statistical strategies to explore how time-varying exposures to heavy metal mixtures affects cognition and cognitive trajectories in children. In chapter 1, we develop a Bayesian model, called Lagged Kernel ...
Quantitative Methods for Stratified Medicine
(2015-05-15)
Stratified medicine has tremendous potential to deliver more effective therapeutic intervention to improve public health. For practical implementation, reliable prediction models and clinically meaningful categorization ...
Physician Preferences for Medical Innovation
(2018-05-15)
Health care spending growth challenges the budgets of governments, businesses, and families. In 2015, one in every six dollars spent in the U.S. economy was related to health care – twice the share in 1980. The rapid growth ...