Pathobiology of Experimental Acute Pancreatitis
Citation
Steer, M. L. 1992. Pathobiology of experimental acute pancreatitis. The Yale Journal of Biology and Medicine 65(5): 421-440.Abstract
Pancreatic duct obstruction, even in the absence of biliary obstruction and/or bile reflux into the pancreatic duct, can trigger acute hemorrhagic necrotizing pancreatitis. The earliest changes are seen within acinar cells. Early derangements in acinar cell biology include inhibition of digestive enzyme secretion and the co-localization of lysosomal hydrolases with digestive enzyme zymogens. Under appropriate conditions, this co-localization could lead to digestive enzyme activation within acinar cells.Other Sources
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2589738/pdf/Terms of Use
This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAACitable link to this page
http://nrs.harvard.edu/urn-3:HUL.InstRepos:4930595
Collections
- HMS Scholarly Articles [17301]
Contact administrator regarding this item (to report mistakes or request changes)