Show simple item record

dc.contributor.authorGnerre, Sante
dc.contributor.authorLander, Eric Steven
dc.contributor.authorLindblad-Toh, Kerstin
dc.contributor.authorJaffe, David B
dc.date.accessioned2011-11-01T14:44:47Z
dc.date.issued2009
dc.identifier.citationGnerre, Sante, Eric S Lander, Kerstin Lindblad-Toh, and David B Jaffe. 2009. Assisted assembly: how to improve a de novo genome assembly by using related species. Genome Biology 10(8): R88.en_US
dc.identifier.issn1465-6906en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:5334258
dc.description.abstractWe describe a new assembly algorithm, where a genome assembly with low sequence coverage, either throughout the genome or locally, due to cloning bias, is considerably improved through an assisting process via a related genome. We show that the information provided by aligning the whole-genome shotgun reads of the target against a reference genome can be used to substantially improve the quality of the resulting assembly.en_US
dc.language.isoen_USen_US
dc.publisherBioMed Centralen_US
dc.relation.isversionofdoi://10.1186/gb-2009-10-8-r88en_US
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745769/pdf/en_US
dash.licenseLAA
dc.titleAssisted Assembly: How to Improve a De Novo Genome Assembly By Using Related Speciesen_US
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden_US
dc.relation.journalGenome Biologyen_US
dash.depositing.authorLander, Eric Steven
dc.date.available2011-11-01T14:44:47Z
dash.affiliation.otherHMS^Systems Biologyen_US
dc.identifier.doi10.1186/gb-2009-10-8-r88*
dash.contributor.affiliatedLander, Eric


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record