Tracking the Culprit: HIV-1 Evolution and Immune Selection Revealed by Single-Genome Amplification

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Tracking the Culprit: HIV-1 Evolution and Immune Selection Revealed by Single-Genome Amplification

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Title: Tracking the Culprit: HIV-1 Evolution and Immune Selection Revealed by Single-Genome Amplification
Author: Brumme, Zabrina L.; Walker, Bruce David

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Citation: Brumme, Zabrina L., and Bruce D. Walker. 2009. Tracking the culprit: HIV-1 evolution and immune selection revealed by single-genome amplification. Journal of Experimental Medicine 206(6): 1215-1218.
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Abstract: Early control of HIV-1 infection is determined by a balance between the host immune response and the ability of the virus to escape this response. Studies using single-genome amplification now reveal new details about the kinetics and specificity of the CD8+ T cell response and the evolution of the virus during early HIV infection.
Published Version: doi://10.1084/jem.20091094
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715053/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:5978763
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