Enantioselective Synthesis of (+)-Cephalostatin 1
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CitationFortner, Kevin, Darryl Kato, Yoshiki Tanaka, Matthew David Shair. 2010. Enantioselective Synthesis of (+)-Cephalostatin 1. Journal of the American Chemical Society 132(1): 275-280.
AbstractThis Article describes an enantioselective synthesis of cephalostatin 1. Key steps of this synthesis are a unique methyl group selective allylic oxidation, directed C−H hydroxylation of a sterol at C12, Au(I)-catalyzed 5-endo-dig cyclization, and a kinetic spiroketalization.
Citable link to this pagehttp://nrs.harvard.edu/urn-3:HUL.InstRepos:7982718
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