A Child with Chronic Manganese Exposure from Drinking Water

DSpace/Manakin Repository

A Child with Chronic Manganese Exposure from Drinking Water

Citable link to this page


Title: A Child with Chronic Manganese Exposure from Drinking Water
Author: Woolf, Alan David; Wright, Robert O.; Amarasiriwardena, Chitra J.; Bellinger, David C.

Note: Order does not necessarily reflect citation order of authors.

Citation: Woolf, Alan, Robert Wright, Chitra Amarasiriwardena, and David Bellinger. 2002. A child with chronic manganese exposure from drinking water. Environmental Health Perspectives 110(6): 613-616.
Full Text & Related Files:
Abstract: The patient's family bought a home in a suburb, but the proximity of the house to wetlands and its distance from the town water main prohibited connecting the house to town water. The family had a well drilled and they drank the well water for 5 years, despite the fact that the water was turbid, had a metallic taste, and left an orange-brown residue on clothes, dishes, and appliances. When the water was tested after 5 years of residential use, the manganese concentration was elevated (1.21 ppm; U.S. Environmental Protection Agency reference, < 0.05 ppm). The family's 10-year-old son had elevated manganese concentrations in whole blood, urine, and hair. The blood manganese level of his brother was normal, but his hair manganese level was elevated. The patient, the 10-year-old, was in the fifth grade and had no history of learning problems; however, teachers had noticed his inattentiveness and lack of focus in the classroom. Our results of cognitive testing were normal, but tests of memory revealed a markedly below-average performance: the patient's general memory index was at the 13th percentile, his verbal memory at the 19th percentile, his visual memory at the 14th percentile, and his learning index at the 19th percentile. The patient's free recall and cued recall tests were all 0.5-1.5 standard deviations (1 SD = 16th percentile) below normal. Psychometric testing scores showed normal IQ but unexpectedly poor verbal and visual memory. These findings are consistent with the known toxic effects of manganese, although a causal relationship cannot necessarily be inferred.
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1240879/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:8156574
Downloads of this work:

Show full Dublin Core record

This item appears in the following Collection(s)


Search DASH

Advanced Search