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dc.contributor.authorTurchin, Alexander
dc.contributor.authorMatheny, Michael E.
dc.contributor.authorShubina, Maria
dc.contributor.authorScanlon, James V.
dc.contributor.authorGreenwood, Bonnie
dc.contributor.authorPendergrass, Merri L.
dc.date.accessioned2012-02-20T01:47:08Z
dc.date.issued2009
dc.identifier.citationTurchin, Alexander, Michael E. Matheny, Maria Shubina, James V. Scanlon, Bonnie Greenwood, and Merri L. Pendergrass. 2009. Hypoglycemia and clinical outcomes in patients with diabetes hospitalized in the general ward. Diabetes Care 32(7): 1153-1157.en_US
dc.identifier.issn0149-5992en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:8191185
dc.description.abstractOBJECTIVE: Hypoglycemia is associated with adverse outcomes in mixed populations of patients in intensive care units. It is not known whether the same risks exist for diabetic patients who are less severely ill. In this study, we aimed to determine whether hypoglycemic episodes are associated with higher mortality in diabetic patients hospitalized in the general ward. RESEARCH DESIGN AND METHODS: This retrospective cohort study analyzed 4,368 admissions of 2,582 patients with diabetes hospitalized in the general ward of a teaching hospital between January 2003 and August 2004. The associations between the number and severity of hypoglycemic (≤50 mg/dl) episodes and inpatient mortality, length of stay (LOS), and mortality within 1 year after discharge were evaluated. RESULTS: Hypoglycemia was observed in 7.7% of admissions. In multivariable analysis, each additional day with hypoglycemia was associated with an increase of 85.3% in the odds of inpatient death (P = 0.009) and 65.8% (P = 0.0003) in the odds of death within 1 year from discharge. The odds of inpatient death also rose threefold for every 10 mg/dl decrease in the lowest blood glucose during hospitalization (P = 0.0058). LOS increased by 2.5 days for each day with hypoglycemia (P < 0.0001). CONCLUSIONS: Hypoglycemia is common in diabetic patients hospitalized in the general ward. Patients with hypoglycemia have increased LOS and higher mortality both during and after admission. Measures should be undertaken to decrease the frequency of hypoglycemia in this high-risk patient population.en_US
dc.language.isoen_USen_US
dc.publisherAmerican Diabetes Associationen_US
dc.relation.isversionofdoi:10.2337/dc08-2127en_US
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699723/pdf/en_US
dash.licenseMETA_ONLY
dc.titleHypoglycemia and Clinical Outcomes in Patients With Diabetes Hospitalized in the General Warden_US
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden_US
dc.relation.journalDiabetes Careen_US
dash.depositing.authorTurchin, Alexander
dash.embargo.until10000-01-01
dash.affiliation.otherHMS^Medicine-Brigham and Women's Hospitalen_US
dash.affiliation.otherHMS^Medicine-Brigham and Women's Hospitalen_US
dc.identifier.doi10.2337/dc08-2127*
dash.contributor.affiliatedTurchin, Alexander
dash.contributor.affiliatedPendergrass, Merri L.


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