The Yield of Head CT in Syncope: A Pilot Study

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The Yield of Head CT in Syncope: A Pilot Study

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Title: The Yield of Head CT in Syncope: A Pilot Study
Author: Bar, J. L.; Mottley, L.; Grossman, Shamai Aaron; Fischer, Christopher M; Lipsitz, Lewis Arnold; Sands, Kenneth Eliot Frederick; Thompson, Sylvia V; Shapiro, Nathan Ivan; Zimetbaum, Peter J.; Thompson, Sally Wright

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Citation: Grossman, S. A., C. Fischer, J. L. Bar, L. A. Lipsitz, L. Mottley, K. Sands, S. Thompson, P. Zimetbaum, and N. I. Shapiro. 2007. The yield of head CT in syncope: a pilot study. Internal and Emergency Medicine 2(1): 46-49.
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Abstract: Although head CT is often routinely performed in emergency department (ED) patients with syncope, few studies have assessed its value. Objectives: To determine the yield of routine head CT in ED patients with syncope and analyse the factors associated with a positive CT. Methods: Prospective, observational, cohort study of consecutive patients presenting with syncope to an urban tertiary-care ED (48 000 annual visits). Inclusion criteria: age >8 and loss of consciousness (LOC). Exclusion criteria included persistent altered mental status, drug-related or post-trauma LOC, seizure or hypoglycaemia. Primary outcome was abnormal head CT including subarachnoid, subdural or parenchymal haemorrhage, infarction, signs of acute stroke and newly diagnosed brain mass. Results: Of 293 eligible patients, 113 (39%) underwent head CT and comprise the study cohort. Ninety-five patients (84%) were admitted to the hospital. Five patients, 5% (95% CI=0.8%–8%), had an abnormal head CT: 2 subarachnoid haemorrhage, 2 cerebral haemorrhage and 1 stroke. Post hoc examination of patients with an abnormal head CT revealed focal neurologic findings in 2 and a new headache in 1. The remaining 2 patients had no new neurologic findings but physical findings of trauma (head lacerations with periorbital ecchymoses suggestive of orbital fractures). All patients with positive findings on CT were >65 years of age. Of the 108 remaining patients who had head CT, 45 (32%–51%) had signs or symptoms of neurologic disease including headache, trauma above the clavicles or took coumadin. Limiting head CT to this population would potentially reduce scans by 56% (47%–65%). If age >60 were an additional criteria, scans would be reduced by 24% (16%–32%). Of the patients who did not have head CT, none were found to have new neurologic disease during hospitalisation or 30-day follow-up. Conclusions: Our data suggest that the derivation of a prospectively derived decision rule has the potential to decrease the routine use of head CT in patients presenting to the ED with syncope.
Published Version: doi://10.1007/s11739-007-0010-5
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