Networking Erythropoiesis

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Networking Erythropoiesis

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Title: Networking Erythropoiesis
Author: Kerenyi, Marc; Orkin, Stuart Holland

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Citation: Kerenyi, Marc A., and Stuart H. Orkin. 2010. Networking erythropoiesis. The Journal of Experimental Medicine 207(12): 2537-2541.
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Abstract: A relatively small cadre of lineage-restricted transcription factors largely orchestrates erythropoiesis, but how these nuclear factors interact to regulate this complex biology is still largely unknown. However, recent technological advances, such as chromatin immunoprecipitation (ChIP) paired with massively parallel sequencing (ChIP-seq), gene expression profiling, and comprehensive bioinformatic analyses, offer new insights into the intricacies of red cell molecular circuits.
Published Version: doi://10.1084/jem.20102260
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