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dc.contributor.authorPuzey, Joshua Robert
dc.contributor.authorKramer, Elena M.
dc.date.accessioned2012-04-06T19:57:14Z
dc.date.issued2009
dc.identifier.citationPuzey, Joshua Robert, and Elena M. Kramer. 2009. Identification of conserved Aquilegia coerulea microRNAs and their targets. Gene 448(1): 46-56.en_US
dc.identifier.issn0378-1119en_US
dc.identifier.issn1879-0038en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:8519268
dc.description.abstractAquilegia is an emerging model organism that is phylogenetically intermediate between the core eudicot and monocot models, Arabidopsis and Oryza. In this study, we have used a comparative genomics approach to identify 45 Aquilegia microRNAs that comprise 20 separate plant microRNA families. We have predicted 84 targets of these newly identified Aquilegia microRNAs including transcription factors and loci involved in metabolism, stress responses, transport, and auxin signaling. microRNA families from 16 plant species and the newly identified microRNAs from Aquilegia were analyzed in a phylogenetic context revealing 40 distantly conserved microRNA families. In addition to these highly conserved plant microRNA families, several families with disjointed phylogenetic distribution were identified. This study provides a phylogenetically important dataset for plant microRNA evolution studies. The current study is the first to identify miRNAs in a lower eudicot in which comprehensive genomic resources are becoming available.en_US
dc.description.sponsorshipOrganismic and Evolutionary Biologyen_US
dc.language.isoen_USen_US
dc.publisherElsevieren_US
dc.relation.isversionofdoi:10.1016/j.gene.2009.08.005en_US
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pubmed/19699282en_US
dash.licenseOAP
dc.subjectAquilegiaen_US
dc.subjectmicroRNAen_US
dc.subjectevolutionen_US
dc.subjectangiospermen_US
dc.titleIdentification of Conserved Aquilegia Coerulea MicroRNAs and Their Targetsen_US
dc.typeJournal Articleen_US
dc.description.versionAuthor's Originalen_US
dc.relation.journalGeneen_US
dash.depositing.authorKramer, Elena M.
dc.date.available2012-04-06T19:57:14Z
dc.identifier.doi10.1016/j.gene.2009.08.005*
dash.contributor.affiliatedPuzey, Joshua
dash.contributor.affiliatedKramer, Elena


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