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dc.contributor.authorMay, Taymaa
dc.contributor.authorGoldstein, Donald Peter
dc.contributor.authorBerkowitz, Ross Stuart
dc.date.accessioned2012-04-09T00:39:55Z
dc.date.issued2011
dc.identifier.citationMay, Taymaa, Donald Peter Goldstein, and Ross Stuart Berkowitz. 2011. Current chemotherapeutic management of patients with gestational trophoblastic neoplasia. Chemotherapy Research and Practice 2011: 806256.en_US
dc.identifier.issn2090-2107en_US
dc.identifier.issn2090-2115en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:8519644
dc.description.abstractGestational trophoblastic neoplasia (GTN) describes a heterogeneous group of interrelated lesions that arise from abnormal proliferation of placental trophoblasts. GTN lesions are histologically distinct, malignant lesions that include invasive hydatidiform mole, choriocarcinoma, placental site trophoblastic tumor (PSTT) and epithelioid trophoblastic tumor (ETT). GTN tumors are generally highly responsive to chemotherapy. Early stage GTN disease is often cured with single-agent chemotherapy. In contrast, advanced stage disease requires multiagent combination chemotherapeutic regimens to achieve a cure. Various adjuvant surgical procedures can be helpful to treat women with GTN. Patients require careful followup after completing treatment and recurrent disease should be aggressively managed. Women with a history of GTN are at increased risk of subsequent GTN, hence future pregnancies require careful monitoring to ensure normal gestational development. This article will review the workup, management and followup of women with all stages of GTN as well as with recurrent disease.en_US
dc.language.isoen_USen_US
dc.publisherHindawi Publishing Corporationen_US
dc.relation.isversionofdoi:10.1155/2011/806256en_US
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265241en_US
dash.licenseLAA
dc.titleCurrent Chemotherapeutic Management of Patients with Gestational Trophoblastic Neoplasiaen_US
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden_US
dc.relation.journalChemotherapy Research and Practiceen_US
dash.depositing.authorMay, Taymaa
dc.date.available2012-04-09T00:39:55Z
dc.identifier.doi10.1155/2011/806256*
dash.contributor.affiliatedGoldstein, Donald
dash.contributor.affiliatedMay, Taymaa
dash.contributor.affiliatedBerkowitz, Ross


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