dc.contributor.author | Gibbs, Karine Alexine | |
dc.contributor.author | Wenren, Larissa Man-Yin | |
dc.contributor.author | Greenberg, E. Peter | |
dc.date.accessioned | 2012-05-06T19:43:38Z | |
dc.date.issued | 2011 | |
dc.identifier.citation | Gibbs, Karine Alexine, Larissa Man-Yin Wenren, and E. Peter Greenberg. 2011. Identity gene expression in Proteus mirabilis. Journal of Bacteriology 193(13): 3286-3292. | en_US |
dc.identifier.issn | 0021-9193 | en_US |
dc.identifier.issn | 1098-5530 | en_US |
dc.identifier.uri | http://nrs.harvard.edu/urn-3:HUL.InstRepos:8667396 | |
dc.description.abstract | Swarming colonies of independent Proteus mirabilis isolates recognize each other as foreign and do not merge together, whereas apposing swarms of clonal isolates merge with each other. Swarms of mutants with deletions in the ids gene cluster do not merge with their parent. Thus, ids genes are involved in the ability of P. mirabilis to distinguish self from nonself. Here we have characterized expression of the ids genes. We show that idsABCDEF genes are transcribed as an operon, and we define the promoter region upstream of idsA by deletion analysis. Expression of the ids operon increased in late logarithmic and early stationary phases and appeared to be bistable. Approaching swarms of nonself populations led to increased ids expression and increased the abundance of ids-expressing cells in the bimodal population. This information on ids gene expression provides a foundation for further understanding the molecular details of self-nonself discrimination in P. mirabilis. | en_US |
dc.description.sponsorship | Molecular and Cellular Biology | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | American Society for Microbiology | en_US |
dc.relation.isversionof | doi:10.1128/JB.01167-10 | en_US |
dc.relation.hasversion | http://www.ncbi.nlm.nih.gov/pubmed/21551301 | en_US |
dash.license | OAP | |
dc.title | Identity Gene Expression in Proteus Mirabilis | en_US |
dc.type | Journal Article | en_US |
dc.description.version | Author's Original | en_US |
dc.relation.journal | Journal of Bacteriology | en_US |
dash.depositing.author | Gibbs, Karine Alexine | |
dc.date.available | 2012-05-06T19:43:38Z | |
dc.identifier.doi | 10.1128/JB.01167-10 | * |
dash.contributor.affiliated | Gibbs, Karine | |
dash.contributor.affiliated | Wenren, Larissa | |