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dc.contributor.authorWestover, Kenneth Dale
dc.contributor.authorWestover, Michael Brandon
dc.contributor.authorWiner, Eric Paul
dc.contributor.authorRichardson, Andrea Lynn
dc.contributor.authorIglehart, James Dirk
dc.contributor.authorPunglia, Rinaa S.
dc.date.accessioned2012-05-09T01:17:42Z
dc.date.issued2011
dc.identifier.citationWestover, Kenneth D., M. Brandon Westover, Eric P. Winer, Andrea L. Richardson, J. Dirk Iglehart, and Rinaa S. Punglia. 2011. Should a sentinel node biopsy be performed in patients with high-risk breast cancer?. International Journal of Breast Cancer 973245.en_US
dc.identifier.issn2090-3170en_US
dc.identifier.issn2090-3189en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:8704123
dc.description.abstractA negative sentinel lymph node (SLN) biopsy spares many breast cancer patients the complications associated with lymph node irradiation or additional surgery. However, patients at high risk for nodal involvement based on clinical characteristics may remain at unacceptably high risk of axillary disease even after a negative SLN biopsy result. A Bayesian nomogram was designed to combine the probability of axillary disease prior to nodal biopsy with customized test characteristics for an SLN biopsy and provides the probability of axillary disease despite a negative SLN biopsy. Users may individualize the sensitivity of an SLN biopsy based on factors known to modify the sensitivity of the procedure. This tool may be useful in identifying patients who should have expanded upfront exploration of the axilla or comprehensive axillary irradiation.en_US
dc.language.isoen_USen_US
dc.publisherSAGE-Hindawi Access to Researchen_US
dc.relation.isversionofdoi:10.4061/2011/973245en_US
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262582/pdf/en_US
dash.licenseLAA
dc.titleShould a Sentinel Node Biopsy Be Performed in Patients with High-Risk Breast Cancer?en_US
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden_US
dc.relation.journalInternational Journal of Breast Canceren_US
dash.depositing.authorPunglia, Rinaa S.
dc.date.available2012-05-09T01:17:42Z
dc.identifier.doi10.4061/2011/973245*
dash.authorsorderedfalse
dash.contributor.affiliatedPunglia, Rinaa
dash.contributor.affiliatedIglehart, James
dash.contributor.affiliatedWestover, Michael
dash.contributor.affiliatedWestover, Kenneth Dale
dash.contributor.affiliatedWiner, Eric
dash.contributor.affiliatedRichardson, Andrea


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