Chiral Sulfinamide/Achiral Sulfonic Acid Cocatalyzed Enantioselective Protonation of Enol Silanes

 
Thumbnail
View/Open
Author
Beck, Elizabeth M.
Hyde, Alan M.
Note: Order does not necessarily reflect citation order of authors.
Published Version
https://doi.org/10.1021/ol201608a
Metadata
Show full item record
Citation
Beck, Elizabeth M., Alan M. Hyde, and Eric N. Jacbosen. 2011. Chiral sulfinamide/achiral sulfonic acid cocatalyzed enantioselective protonation of enol silanes. Organic Letters 13(16): 4260-4263.
Abstract
The application of chiral sulfinamides and achiral sulfonic acids as a co-catalyst system for enantioselective protonation reactions is described. Structurally simple, easily accessible sulfinamides were found to induce moderate-to-high eeʼs in the formation of 2-aryl-substituted cycloalkanones from the corresponding trimethylsilyl enol ethers.
Other Sources
https://www.ncbi.nlm.nih.gov/pubmed/21786775
Terms of Use
This article is made available under the terms and conditions applicable to Open Access Policy Articles, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#OAP
Citable link to this page
http://nrs.harvard.edu/urn-3:HUL.InstRepos:8737993

Collections