Optogenetics and Computer Vision for C. elegans Neuroscience and Other Biophysical Applications
MetadataShow full item record
CitationLeifer, Andrew. 2011. Optogenetics and Computer Vision for C. elegans Neuroscience and Other Biophysical Applications. Doctoral dissertation, Harvard University.
AbstractThis work presents optogenetics and real-time computer vision techniques to non-invasively manipulate and monitor neural activity with high spatiotemporal resolution in awake behaving Caenorhabditis elegans. These methods were employed to dissect the nematode's mechanosensory and motor circuits and to elucidate the neural control of wave propagation during forward locomotion. Additionally, similar computer vision methods were used to automatically detect and decode fluorescing DNA origami nanobarcodes, a new class of fluorescent reporter constructs.
Citable link to this pagehttp://nrs.harvard.edu/urn-3:HUL.InstRepos:9276708
- FAS Theses and Dissertations 
Contact administrator regarding this item (to report mistakes or request changes)