Sedgh, GildaSpiegelman, DonnaLarsen, UllaMsamanga, GernardFawzi, Wafaie W.2019-09-212004Sedgh, Gilda, Donna Spiegelman, Ulla Larsen, Gernard Msamanga, and Wafaie W Fawzi. 2004. “Breastfeeding and Maternal HIV-1 Disease Progression and Mortality.” AIDS 18 (7): 1043–49. https://doi.org/10.1097/00002030-200404300-00013.0269-93701473-5571http://nrs.harvard.edu/urn-3:HUL.InstRepos:41384723Objective: To examine the association between breastfeeding and disease progression among HIV-infected women in Dares Salaam, Tanzania. Design and methods: Cohort study design with Cox proportional hazards models. Results: The relative risk of death comparing women who recently had been breastfeeding to those who were not breastfeeding was 0.47 (95% confidence interval, 0.18-1.20). Neither breastfeeding status nor the duration of exclusive or partial breastfeeding was associated with HIV-1 disease progression, represented by death or development of a low CD4 cell count, anemia or excessive weight loss, in multivariate analyses. These associations remained insignificant when women with relatively low and high CD4 cell counts were analyzed separately. Conclusion: There is insufficient evidence to support the hypothesis that breastfeeding is detrimental to the health of HIV-infected women.en-USJournal Article2019-09-2110.1097/00002030-200404300-00013