Shahar, D. R.Schwarzfuchs, D.Fraser, D.Vardi, H.Thiery, J.Fiedler, G. M.Bluher, M.Stumvoll, M.Stampfer, MeirShai, I.2019-09-052010Shahar, Danit R, Dan Schwarzfuchs, Drora Fraser, Hillel Vardi, Joachim Thiery, Georg Martin Fiedler, et al. 2010. “Dairy Calcium Intake, Serum Vitamin D, and Successful Weight Loss.” The American Journal of Clinical Nutrition 92 (5): 1017–22. https://doi.org/10.3945/ajcn.2010.29355.0002-91651938-3207http://nrs.harvard.edu/urn-3:HUL.InstRepos:41292621Background The role 01 dairy calcium intake and scrum vitamin D concentrations in weight loss is controversialObjective The objective was to assess the association of dairy calcium intake and serum vitamin D with weight lossDesign We analyzed data from participants in the 2 y Dietary Intervention Randomized Controlled Trial (DIRECT) [n = 322 mean body mass index (BMI in kg/m(2)) 31 mean age 52 y] A representative sample (n = 126) was followed for 6 mo for serum vitamin D changesResults Baseline serum 25 hydroxyvitamin D [25(OH)D] concentrations decreased significantly across the tertiles of baseline BMI (25 6 +/- 8 0 24 1 +/- 8 9 and 22 9 +/- 6 8 ng/mL respectively P for trend = 0 02) Baseline concentrations of vitamin D and dairy calcium intake were not associated with subsequent weight loss How ever in repeated-measures models adjusted for age sex baseline BMI total tat intake and diet group assignment higher 6 mo tertile levels of dairy calcium intake (median for tertiles 156 5 358 0 and 582 9 mg/d respectively) and serum 25(OH)D (14 5 21 2 and 30 2 ng/mL respectively) were associated with increased weight loss across the 2 y intervention (-3 3 -3 5 and -5 3 kg respectively for dairy calcium P = 0 043 -3 1 -3 8, and -5 6 kg respectively for vitamin D, P = 0 013) In a multivariate logistic regression adjusted simultaneously for age sex baseline BMI total fat intake diet group vitamin D concentration and dairy calcium an increase of 1 SD in dairy calcium intake increased the likelihood of weight loss of >4 5 kg in the preceding 6 mo [odds ratio (OR) 1 45 P = 0 046] A similir increase was seen for serum 25(OH)D at the 6 mo point (OR 1 7 P = 0 009)Conclusion Our study suggests that both higher dairy calcium in take and increased serum vitamin D are related to greater diet-induced weight loss This trial was registered at clinicaltrials gov as NCT00160108 Am J Clin Nutr 2010 92 1017-22en-USJournal Article2019-09-0510.3945/ajcn.2010.29355