Gutin, A. M.Abkevich, V. I.Shakhnovich, E. I.2019-09-271996Gutin, A. M., V. I. Abkevich, and E. I. Shakhnovich. 1996. “Chain Length Scaling of Protein Folding Time.” Physical Review Letters 77 (27): 5433–36. https://doi.org/10.1103/physrevlett.77.5433.0031-90071079-71141092-0145http://nrs.harvard.edu/urn-3:HUL.InstRepos:41417268Folding of protein-like heteropolymers into unique 3D structures is investigated using Monte Carlo simulations on a cubic lattice. We found that the folding time of chains of length N scales as N-lambda at the temperature of fastest folding. For chains with random sequences of monomers lambda approximate to 6, and for chains with sequences designed to provide a pronounced minimum of energy to their ground state conformation lambda approximate to 4. Folding at low temperatures exhibits a simple, Arrhenius-like behavior.en-USJournal Article2019-09-2710.1103/PhysRevLett.77.5433