Proposed Structure of the Neocarzinostatin Chromophore-Methyl Thioglycolate Adduct; A Mechanism for the Nucleophilic Activation of Neocarzinostatin

Myers, Andrew2009-07-291987Myers, Andrew G. 1987. Proposed structure of the neocarzinostatin chromophore-methyl thioglycolate adduct; A mechanism for the nucleophilic activation of neocarzinostatin. Tetrahedron Letters 28(39): 4493-4496.0040-4039http://nrs.harvard.edu/urn-3:HUL.InstRepos:3202345Structure 1 is proposed to represent the product of reaction of methyl thioglycolate with the neocarzinostatin chromophore. A mechanism for the formation of 1 is presented which provides a rationale for the nucleophilic activation of neocarzinostatin.en-USnecleophilic activationneocarzinostatin chromophoremethyl thioglycolateProposed Structure of the Neocarzinostatin Chromophore-Methyl Thioglycolate Adduct; A Mechanism for the Nucleophilic Activation of NeocarzinostatinJournal Article10.1016/S0040-4039(00)96545-6