Deamer, David W.Branton, Daniel2009-07-012002Deamer, David W. and Daniel Branton. 2002. Characterization of nucleic acids by nanopore analysis. Accounts of Chemical Research 35(10): 817-825.0001-4842http://nrs.harvard.edu/urn-3:HUL.InstRepos:3137806Single-stranded DNA and RNA molecules in solution can be driven through a nanoscopic pore by an applied electric field. As each molecule occupies the pore, a characteristic blockade of ionic current is produced. Information about length, composition, structure, and dynamic motion of the molecule can be deduced from modulations of the current blockade.en-USCharacterization of Nucleic Acids by Nanopore AnalysisJournal Article10.1021/ar000138m