Myers, AndrewYang, Bryant H.Kopecky, David J.2011-02-151996Myers, Andrew G., Bryant Yang, and David Kopecky. 1996. Lithium Amidotrihydroborate, a Powerful New Reductant. Transformation of Tertiary Amides to Primary Alcohols. Tetrahedron Letters 37, no. 21: 3623-3626.0040-4039http://nrs.harvard.edu/urn-3:HUL.InstRepos:4725865Lithium amidotrihydroborate (LiH3NBH3, LAB) is a new and highly nucleophilic reducing agent that is easily prepared by deprotonation of the commercial reagent borane-ammonia complex (H3NBH3) with n-BuLi in tetrahydrofuran (THF) at 0 degrees C. LAB is found to be a superior reagent for the transformation of tertiary amides into the corresponding primary alcohols.en-USprimary alcoholstertiary amidesreductantlithium amidotrihydroborate2011-02-1510.1016/0040-4039(96)00652-1