Ramanathan, ArvindSchreiber, Stuart2010-10-052007Ramanathan, Arvind and Stuart L. Schreiber. 2007. Multilevel regulation of growth rate in yeast revealed using systems biology. Journal of Biology 6:3.1478-5854http://nrs.harvard.edu/urn-3:HUL.InstRepos:4457663The effect of changing growth rates on the transcriptome, proteome and metabolome has been systematically studied. Measurements made under varying nutrient conditions, corresponding to biochemical pathways that correlate primarily with growth rate, reveal a central role for mitochondrial metabolism and the TOR (target of rapamycin) signaling pathway.en-USMultilevel Regulation of Growth Rate in Yeast Revealed Using Systems BiologyJournal Article2010-10-0510.1186/jbiol56