Qiu, WeiliangLee, Mei-Ling Ting2012-02-142006Qiu, Weiliang, and Mei-Ling Ting Lee. 2006. SPCalc: A web-based calculator for sample size and power calculations in micro-array studies. Bioinformation 1(7): 251-252.0973-2063http://nrs.harvard.edu/urn-3:HUL.InstRepos:8160851Calculation of the appropriate sample size in planning microarray studies is important because sample collection can be expensive and time-consuming. Sample-size calculation is also a challenging issue for microarray studies because the number of genes is far larger than the number of samples so that traditional methods of sample-size calculation cannot be directly applied. To help investigators answer the question of how many samples are needed in their microarray studies, we developed a user-friendly web-based calculator, SPCalc, for calculating sample size and power for a variety of commonly used experimental designs, including completely randomized treatment control design, matched-pairs design, multiple-treatment design having an isolated treatment effect, and randomized block design.en-USgene expressionmicroarraysample sizepower calculationJournal Article2012-02-1410.6026/97320630001251