Rao, SridharOrkin, Stuart2012-12-112006Rao, Sridhar, and Stuart H. Orkin. 2006. Unraveling the transcriptional network controlling ES cell pluripotency. Genome Biology 7(8): 230.1465-6906http://nrs.harvard.edu/urn-3:HUL.InstRepos:10024402Embryonic stem cells (ES cells) are powerful tools for genetic engineering and hold significant potential for regenerative medicine. Recent work provides new insights into ES cell pluripotency and delineates separate transcriptional pathways in ES cells for maintenance of the undifferentiated state and for self-renewal.en-USSTAT3embryonic stem cellsself-renewalmammalian embryodifferentiationexpressioninductionfusionOct4NanogCommentary or Review2012-12-1110.1186/gb-2006-7-8-230