Brumme, Zabrina L.Walker, Bruce2012-01-032009Brumme, Zabrina L., and Bruce D. Walker. 2009. Tracking the culprit: HIV-1 evolution and immune selection revealed by single-genome amplification. Journal of Experimental Medicine 206(6): 1215-1218.0022-1007http://nrs.harvard.edu/urn-3:HUL.InstRepos:5978763Early control of HIV-1 infection is determined by a balance between the host immune response and the ability of the virus to escape this response. Studies using single-genome amplification now reveal new details about the kinetics and specificity of the CD8+ T cell response and the evolution of the virus during early HIV infection.en-USJournal Article2012-01-0310.1084/jem.20091094