Robasky, KimberlyBulyk, Martha2011-03-192010Robasky, Kimberly, and Martha L. Bulyk. 2011. UniPROBE, update 2011: expanded content and search tools in the online database of protein-binding microarray data on proteinâ DNA interactions. Nucleic Acids Research 39(Database issue): D124-D128.0305-1048http://nrs.harvard.edu/urn-3:HUL.InstRepos:4745741The Universal PBM Resource for Oligonucleotide-Binding Evaluation (UniPROBE) database is a centralized repository of information on the DNA-binding preferences of proteins as determined by universal protein-binding microarray (PBM) technology. Each entry for a protein (or protein complex) in UniPROBE provides the quantitative preferences for all possible nucleotide sequence variants (‘words’) of length k (‘k-mers’), as well as position weight matrix (PWM) and graphical sequence logo representations of the k-mer data. In this update, we describe >130% expansion of the database content, incorporation of a protein BLAST (blastp) tool for finding protein sequence matches in UniPROBE, the introduction of UniPROBE accession numbers and additional database enhancements. The UniPROBE database is available at http://uniprobe.org.en-USJournal Article2011-03-1910.1093/nar/gkq992