Moriguchi, HisashiZhang, YueMihara, MakotoSato, Chifumi2012-04-262012Moriguchi, Hisashi, Yue Zhang, Makoto Mihara, and Chifumi Sato. 2012. A therapeutic method for the direct reprogramming of human liver cancer cells with only chemicals. Scientific Reports 2: 280.2045-2322http://nrs.harvard.edu/urn-3:HUL.InstRepos:8623556Various methods for the direct reprogramming of human somatic cells have been developed. However, a therapeutic method to reprogram and eliminate human solid tumor cells has not been developed. Here we show a novel therapeutic method to reprogram and eliminate human solid tumor cells with chemicals. This therapeutic method may be applicable to various human solid tumor cells that express aldo-keto reductase family 1 member B10 (AKR1B10) and retinoid X receptors (RXRs).en-USJournal Article2012-04-2610.1038/srep00280