Jacobsen, EricBeck, Elizabeth M.Hyde, Alan M.2012-05-142011Beck, Elizabeth M., Alan M. Hyde, and Eric N. Jacbosen. 2011. Chiral sulfinamide/achiral sulfonic acid cocatalyzed enantioselective protonation of enol silanes. Organic Letters 13(16): 4260-4263.1523-7060http://nrs.harvard.edu/urn-3:HUL.InstRepos:8737993The application of chiral sulfinamides and achiral sulfonic acids as a co-catalyst system for enantioselective protonation reactions is described. Structurally simple, easily accessible sulfinamides were found to induce moderate-to-high eeʼs in the formation of 2-aryl-substituted cycloalkanones from the corresponding trimethylsilyl enol ethers.en-USpolyphenyl derivativesdiastereoselective synthesesenantioselective synthesescycloalkylphenyl derivativesJournal Article2012-05-1410.1021/ol201608a