Hur, Kyu YeonSo, Jae-SeonRuda, VeraFrank-Kamenetsky, MariaFitzgerald, KevinKoteliansky, VictorIwawaki, TakaoGlimcher, LaurieLee, Ann-Hwee2013-03-252012Hur, Kyu Yeon, Jae-Seon So, Vera Ruda, Maria Frank-Kamenetsky, Kevin Fitzgerald, Victor Koteliansky, Takao Iwawaki, Laurie H. Glimcher, and Ann-Hwee Lee. 2012. IRE1α activation protects mice against acetaminophen-induced hepatotoxicity. The Journal of Experimental Medicine 209(2): 307-318.0022-10071540-9538http://nrs.harvard.edu/urn-3:HUL.InstRepos:10463939Mice lacking the transcription factor XBP1 exhibit constitutive activation of the stress sensor IRE1α and are protected from acetaminophen overdose–induced acute liver failure.en-USJournal Article2013-03-2510.1084/jem.20111298