Villablanca Bradanovic, Eduardo Javier2013-05-022013Villablanca, Eduardo J. 2013. Retinoic acid-producing DCs and gut-tropic \(FOXP3^+\) regulatory T cells in the induction of oral tolerance. Oncoimmunology 2(2): e22987.2162-4011http://nrs.harvard.edu/urn-3:HUL.InstRepos:10610231The systemic unresponsiveness of the immune system to orally administered antigens is known as oral tolerance. Recent findings describe a new step for the induction of oral tolerance, consisting in the homing of \(FOXP3^+\) regulatory T cells to the small bowel and the local acquisition of full immunosuppressive capacities, a process in which retinoic acid-producing dendritic cells might play a crucial role.en-USFOXP3dendritic cellsgut homingoral toleranceretinoic acidJournal Article2013-05-0210.4161/onci.22987