Hladish, ThomasMelamud, EugeneBarrera, Luis A.Galvani, AlisonMeyers, Lauren Ancel2013-04-222012Hladish, Thomas, Eugene Melamud, Luis Alberto Barrera, Alison Galvani, and Lauren Ancel Meyers. 2012. EpiFire: An open source C++ library and application for contact network epidemiology. BMC Bioinformatics 13:76.1471-2105http://nrs.harvard.edu/urn-3:HUL.InstRepos:10579231Background: Contact network models have become increasingly common in epidemiology, but we lack a flexible programming framework for the generation and analysis of epidemiological contact networks and for the simulation of disease transmission through such networks. Results: Here we present EpiFire, an applications programming interface and graphical user interface implemented in C++, which includes a fast and efficient library for generating, analyzing and manipulating networks. Network-based percolation and chain-binomial simulations of susceptible-infected-recovered disease transmission, as well as traditional non-network mass-action simulations, can be performed using EpiFire. Conclusions: EpiFire provides an open-source programming interface for the rapid development of network models with a focus in contact network epidemiology. EpiFire also provides a point-and-click interface for generating networks, conducting epidemic simulations, and creating figures. This interface is particularly useful as a pedagogical tool.en-USJournal Article2013-04-2210.1186/1471-2105-13-76