van Rijn, SjoerdNilsson, JonasNoske, David P.Vandertop, W. PeterTannous, BakhosWürdinger, Thomas2013-05-132013Van Rijn, Sjoerd, Jonas Nilsson, David P. Noske, W. Peter Vandertop, Bakhos A. Tannous, and Thomas Würdinger. 2013. Functional multiplex reporter assay using tagged Gaussia luciferase. Scientific Reports 3: 1046.2045-2322http://nrs.harvard.edu/urn-3:HUL.InstRepos:10622999We have developed a multiplex reporter system to monitor multiple biological variables in real-time. The secreted Gaussia luciferase was fused to ten different epitope tags (Gluc\(_{tag}\)), each expressed in different tumor cells. By immunobinding of the tags followed by Gluc\(_{tag}\) detection, this system allowed the independent and real-time monitoring of mixed cell cultures in vitro and of mixed subcutaneous and intracranial tumor subpopulations in vivo.en-USJournal Article2013-05-1310.1038/srep01046