Greenberg, Michael EldonMardinly, Alan Robert2013-10-082013-10-082013Mardinly, Alan Robert. 2013. Regulation of Synapse Development by Activity Dependent Transcription in Inhibitory Neurons. Doctoral dissertation, Harvard University.http://dissertations.umi.com/gsas.harvard:10739http://nrs.harvard.edu/urn-3:HUL.InstRepos:11151534Neuronal activity and subsequent calcium influx activates a signaling cascade that causes transcription factors in the nucleus to rapidly induce an early-response program of gene expression. This early-response program is composed of transcriptional regulators that in turn induce transcription of late-response genes, which are enriched for regulators of synaptic development and plasticity that act locally at the synapse.en-USNeurosciencesActivityInhibitionNpas4somatostatinsynapse developmentThesis or Dissertation2014-06-07