Hooker, ChristineTully, Laura Magdalen2013-10-182013-10-182013Tully, Laura Magdalen. 2013. Cognitive Control of Emotional Information in Schizophrenia: Understanding the Mechanisms of Social Functioning Impairments. Doctoral dissertation, Harvard University.http://dissertations.umi.com/gsas.harvard:11105http://nrs.harvard.edu/urn-3:HUL.InstRepos:11181223Social functioning impairments are a core, debilitating, and treatment refractory feature of schizophrenia. The mechanisms contributing to these impairments are unknown. Cognitive control mechanisms, mediated by the lateral prefrontal cortex (LPFC), are known to influence response to interpersonal stressors in healthy individuals, thus impairments in these processes may contribute to social deficits. Deficits in cognitive control and lateral prefrontal abnormalities are well-documented in schizophrenia, but the relationship between these deficits and social interactions has received limited attention in the literature. The current dissertation presents a systematic examination of the contribution of the behavioral and neural mechanisms of cognitive control to social functioning impairments in schizophrenia. Three papers are presented.en-USClinical psychologyCognitive psychologycognitive controlexperience samplingfMRIschizophreniasocial cognitionsocial functioningCognitive Control of Emotional Information in Schizophrenia: Understanding the Mechanisms of Social Functioning ImpairmentsThesis or Dissertation2015-10-10