Greig, Luciano CustoWoodworth, Mollie AnnGalazo, MariaPadmanabhan, HariMacklis, Jeffrey2014-03-032013Greig, Luciano Custo, Mollie B. Woodworth, Maria J. Galazo, Hari Padmanabhan, and Jeffrey D. Macklis. 2013. “Molecular Logic of Neocortical Projection Neuron Specification, Development and Diversity.” Nat Rev Neurosci 14 (11) (October 9): 755–769. doi:10.1038/nrn3586. http://dx.doi.org/10.1038/nrn3586.1471-003Xhttp://nrs.harvard.edu/urn-3:HUL.InstRepos:11857763The sophisticated circuitry of the neocortex is assembled from a diverse repertoire of neuronal subtypes generated during development under precise molecular regulation. In recent years, several key controls over the specification and differentiation of neocortical projection neurons have been identified. This work provides substantial insight into the 'molecular logic' underlying cortical development and increasingly supports a model in which individual progenitor-stage and postmitotic regulators are embedded within highly interconnected networks that gate sequential developmental decisions. Here, we provide an integrative account of the molecular controls that direct the progressive development and delineation of subtype and area identity of neocortical projection neurons.en-USJournal Article2014-02-24Custo Greig L, Woodworth MB, Galazo MJ, Padmanabhan H, Macklis JD2014-03-0310.1038/nrn3586