Garber, Alan2014-01-281989Garber, Alan M. 1989. A discrete-time model of the acquisition of antibiotic-resistant infections in hospitalized patients. Biometrics 45, no. 3:797-816.0006-341Xhttp://nrs.harvard.edu/urn-3:HUL.InstRepos:11595739Antibiotic use is thought to promote bacterial antibiotic resistance by selectively inhibiting the growth of sensitive strains. This study investigates the relation between antibiotic use and the propagation of antibiotic-resistant hospital-acquired infections due to gram-negative bacteria in a population of hospitalized patients. It treats infection spread and hospital mortality as a Markov process, in which the transition probabilities are logistic functions of a set of personal and hospital characteristics. Data from a university hospital are used to derive the parameters of the model.en-USJournal Article2013-12-17Garber AM10.2307/2531684