Cheema, Tooba AFecci, PeterNing, JianfangRabkin, Samuel2014-03-112014Cheema, Tooba A, Peter E Fecci, Jianfang Ning, and Samuel D Rabkin. 2014. “Immunovirotherapy for the treatment of glioblastoma.” Oncoimmunology 3 (1): e27218. doi:10.4161/onci.27218. http://dx.doi.org/10.4161/onci.27218.2162-4011http://nrs.harvard.edu/urn-3:HUL.InstRepos:11879877We have recently described a new murine model of glioblastoma, generated by the implantation of syngeneic glioblastoma stem cells into immunocompetent mice, that recapitulates the salient histopathological and immunological features of the human disease. We employed this model to demonstrate the multifaceted activity of an oncolytic herpes simplex virus genetically modified to express interleukin-12, G47∆-IL12.en-UScancer stem cellsgliomaherpes simplex virusinterleukin-12oncolytic virusTregJournal Article2014-03-1110.4161/onci.27218