Beyer, JohannaHadwiger, MarkusAl-Awami, AliJeong, Won-KiKasthuri, NarayananLichtman, JeffPfister, Hanspeter2014-03-122013Beyer, Johanna, Markus Hadwiger, Ali Al-Awami, Won-Ki Jeong, Narayanan Kasthuri, Jeff W. Lichtman, and Hanspeter Pfister. 2013. “Exploring the Connectome: Petascale Volume Visualization of Microscopy Data Streams.” IEEE Computer Graphics and Applications 33 (4): 50–61. doi:10.1109/mcg.2013.55. http://dx.doi.org/10.1109/MCG.2013.55.0272-1716http://nrs.harvard.edu/urn-3:HUL.InstRepos:11880287Recent advances in high-resolution microscopy let neuroscientists acquire neural-tissue volume data of extremely large sizes. However, the tremendous resolution and the high complexity of neural structures present big challenges to storage, processing, and visualization at interactive rates. A proposed system provides interactive exploration of petascale (petavoxel) volumes resulting from high-throughput electron microscopy data streams. The system can concurrently handle multiple volumes and can support the simultaneous visualization of high-resolution voxel segmentation data. Its visualization-driven design restricts most computations to a small subset of the data. It employs a multiresolution virtual-memory architecture for better scalability than previous approaches and for handling incomplete data. Researchers have employed it for a 1-teravoxel mouse cortex volume, of which several hundred axons and dendrites as well as synapses have been segmented and labeled.en-USJournal Article2014-03-12Jeff Lichtman2014-03-1210.1109/mcg.2013.55