Chaperones as thermodynamic sensors of drug–target interactions reveal kinase inhibitor specificities in living cells

Taipale, MikkoKrykbaeva, IrinaWhitesell, LukeSantagata, SandroZhang, JianmingLiu, QingsongGray, NathanaelLindquist, Susan2014-03-112013Taipale, Mikko, Irina Krykbaeva, Luke Whitesell, Sandro Santagata, Jianming Zhang, Qingsong Liu, Nathanael S. Gray, and Susan Lindquist. 2013. “Chaperones as thermodynamic sensors of drug–target interactions reveal kinase inhibitor specificities in living cells.” Nature biotechnology 31 (7): 630-637. doi:10.1038/nbt.2620. http://dx.doi.org/10.1038/nbt.2620.1087-0156http://nrs.harvard.edu/urn-3:HUL.InstRepos:11879466en-USChaperones as thermodynamic sensors of drug–target interactions reveal kinase inhibitor specificities in living cellsJournal Article2014-03-1110.1038/nbt.2620