Lin, XihongBarnett, Ian2014-06-062014-06-062014Barnett, Ian. 2014. SNP-set Tests for Sequencing and Genome-Wide Association Studies. Doctoral dissertation, Harvard University.http://dissertations.umi.com/gsas.harvard:11416http://nrs.harvard.edu/urn-3:HUL.InstRepos:12274530In this dissertation we propose methodology for testing SNP-sets for genetic associations, both for sequencing and genome-wide association studies. Due to the large scale of this kind of data, there is an emphasis on producing methodology that is not only accurate and powerful, but also computationally efficient.en-USBiostatisticsgenome-wide association studieshigher criticismsequencingSNP-set testingThesis or Dissertation2014-06-06