Synthetic Studies toward Hennoxazole A. Use of a Selective Bisoxazole Alkylation as the Key Fragment Coupling

Smith, Thomas E.Balskus, Emily2017-09-252002E. Smith, Thomas, and Emily P. Balskus. 2002. “Synthetic Studies Toward Hennoxazole A. Use of a Selective Bisoxazole Alkylation as the Key Fragment Coupling.” HETEROCYCLES 57 (7): 1219. doi:10.3987/com-02-9480.0385-5414http://nrs.harvard.edu/urn-3:HUL.InstRepos:33946915A model system for side chain fragment coupling to the core of hennoxazole A is investigated. Lateral metallation of a C13-TBS-protected bisoxazole, using lithium diethylamide, allows for selective and efficient alkylation at C15.en-USSynthetic Studies toward Hennoxazole A. Use of a Selective Bisoxazole Alkylation as the Key Fragment CouplingJournal Article2017-09-2510.3987/COM-02-9480