Palladium(III)-Catalyzed Fluorination of Arylboronic Acid Derivatives

Mazzotti, Anthony RenatoCampbell, Michael GlennTang, PingpingMurphy, JenniferRitter, Tobias2014-06-172013Mazzotti, Anthony R., Michael G. Campbell, Pingping Tang, Jennifer M. Murphy, and Tobias Ritter. 2013. Palladium(III)-Catalyzed Fluorination of Arylboronic Acid Derivatives. Journal of the American Chemical Society 135, no. 38: 14012–14015.0002-78631520-5126http://nrs.harvard.edu/urn-3:HUL.InstRepos:12330896A practical, palladium-catalyzed synthesis of aryl fluorides from arylboronic acid derivatives is presented. The reaction is operationally simple and amenable to multigram-scale synthesis. Evaluation of the reaction mechanism suggests a single-electron-transfer pathway, involving a Pd(III) intermediate that has been isolated and characterized.en-USPalladium(III)-Catalyzed Fluorination of Arylboronic Acid DerivativesJournal Article2014-06-1710.1021/ja405919z