Behar, Samuel MauriceRothchild, Alissa Chen2014-06-062014-06-062014Rothchild, Alissa Chen. 2014. Antimicrobial Roles for iNKT Cells and GM-CSF in Mycobacterium Tuberculosis Infection. Doctoral dissertation, Harvard University.http://dissertations.umi.com/gsas.harvard:11371http://nrs.harvard.edu/urn-3:HUL.InstRepos:12271798Despite effective antibiotics, Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, still infects nearly one-third of the world's population. While key immune factors including CD4+ T cells and IFNg production have been identified, there are still many antimicrobial mechanisms yet to be explored. Here we characterized the role of invariant natural killer T (iNKT) cells and GM-CSF during Mtb infection.en-USGM-CSFimmunologyiNKT cellsMtbTuberculosisThesis or Dissertation2016-06-04