Livingston, David MorseHill, Sarah2014-06-062014-06-062014Hill, Sarah James. 2014. New insights into BRCA1 function and its role in cancer development. Doctoral dissertation, Harvard University.http://dissertations.umi.com/gsas.harvard:11625http://nrs.harvard.edu/urn-3:HUL.InstRepos:12274574BRCA1 is a breast and ovarian tumor suppressor. The role of BRCA1 in the repair of double strand DNA breaks by homologous recombination [HR] is its best understood function and the function most often implicated in BRCA1 breast cancer suppression. However, BRCA1 has less well defined roles in multiple other molecular processes.en-USGeneticsThesis or Dissertation2014-06-06